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Principal Investigator
Aibo Wu Ph.D., Professor
Laboratory of Mycotoxin Research and Food Safety

E-mail: abwu@@sibs.ac.cn (delete one @ to send email)

Education Background & Academic Experience:
Dr. Wu obtained Ph. D. from Huazhong Agricultural University in Jan., 2005. Afterwards, starting from Apr., 2005, he was a lecturer and two years later promoted to associate professor at School of Life Sciences and Biotechnology, Shanghai Jiao Tong University. From Apr. 2011, he was invited as associate professor and two years later as full professor to establish the group of Mycotoxin Research at Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences. From Feb., 2015, he joined INS in October 2005, as a Principal Investigator, Professor of the Laboratory of Mycotoxin Research and Food Safety at INS, SIBS/CAS. As achieved, he has published 45 peer-reviewed full-text articles and co-acquired one provincial level I Science & Technology Advancement Award.

Research Interests:
(1) Development of the models for risk assessment on co-occurring mycotoxin contaminants originated from fungal isolates in various foods, via the systems of animal mouse and cell lines.
(2) Establishment and validation of chromatographic approaches (LC-MS/MS) and immunological assays for multi-component mycotoxins in a series of food matrices.
(3) Population structure of mycotoxin-producing Fusarium species and regulatory mechanism of mycotoxin production in foods, as well as novel nano-materials and natural anti-toxic strains for detoxification and neutralization of mycotoxin contaminants in the whole chain concerning food safety.

Research Team:

Selected Publications:

  1. Na Liu, Dongxia Nie, Yanglan Tan, Zhiyong Zhao, Yucai Liao, Hui Wang , Sarah De Saeger, Aibo Wu*. An ultrasensitive Electrochemical Immunosensor Based on Antibody Oriented Immobilization for Family Zearalenones Determination. Microchim Acta, 2017,184:147-153.
  2. Wen Shi, Yanglan Tan, Shuangxia Wang, Donald Gardiner, Sarah De Saeger, Yucai Liao, Cheng Wang, Yingying Fan, Zhouping Wang*, Aibo Wu*. Mycotoxigenic Potentials of Fusarium Species in Various Culture Matrices Revealed by Mycotoxin Profiling. Toxins, 2016, doi:10.3390/toxins9010006.
  3. Ye Tian, Yanglan Tan, Na Liu, Zheng Yan, Yucai Liao, Jie Chen, Sarah de Saeger, Hua Yang, Qiaoyan Zhang and Aibo Wu*. Detoxification of Deoxynivalenol via Glycosylation Represents Novel Insights on Antagonistic Activities of Trichoderma when Confronted with Fusarium graminearum. Toxins, 2016, 8, 335; doi:10.3390/toxins8110335.
  4. Ye Tian, Yanglan Tan, Yucai Liao, Changpo Sun, Shuangxia Wang, Aibo Wu*. Functional agents to biologically control deoxynivalenol contamination incereal grains. Frontiers in Microbiology, 2016, 7: 395.
  5. Na Liu, Zhiyong Zhao, Yanglan Tan, Lei Lu, Lin Wang, Yucai Liao, Natalia Beloglazova, Sarah De Saeger, Xiaodong Zheng*, Aibo Wu*. Simultaneous raising of rabbit monoclonal antibodies to fluoroquinolones with diverse recognition functionalities via single mixture immunization. Analytical Chemistry, 2016, 88: 1246-1252.
  6. Zhiyong Zhao, Na Liu, Lingchen Yang, Jianhua Wang, Suquan Song, Dongxia Nie, Xianli Yang, Jiafa Hou, Aibo Wu*. Cross-linked chitosan polymers as generic adsorbents for simultaneous adsorption of multiple mycotoxins. Food Control, 2015, 57: 362-369.
  7. Na Liu, Dongxia Nie, Zhiyong Zhao, Xianjun Meng, Aibo Wu*. Ultrasensitive immunoassays based on biotinestreptavidin amplified system for quantitative determination of family zearalenones. Food Control, 2015, 57: 202-209.
  8. Wenshuo Sun, Zheng Han; Aerts Johan, Dongxia Nie, Mengtong Jin, Wen Shi, Zhiyong Zhao, Sarah De Saeger, Yong Zhao*, Aibo Wu*. A reliable liquid chromatographyCtandem mass spectrometry method for simultaneous determination of multiple mycotoxins in fresh fish and dried seafoods. Journal of Chromatography A, 2015, 1387:42-48.
  9. Suquan Song, Na Liu, Zhiyong Zhao, Emmanuel Njumbe Ediage, Songling Wu, Changpo Sun, Sarah De Saeger, Aibo Wu*. Multiplex Lateral Flow Immunoassay for Mycotoxin Determination. Analytical Chemistry, 2014, 86:4995-5001.
  10. Zheng Han, Dongxia Nie, Emmanuel Njumbe Ediage, Xianli Yang, JianhuaWang, Bo Chen, Shuguang Li, Stephen L.W. On, Sarah De Saeger, Aibo Wu*. Cumulative health risk assessment of co-occurring mycotoxins of deoxynivalenol and its acetyl derivatives in wheat and maize: case study, Shanghai, China Food and Chemical Toxicology, 2014, 74: 334C342.
  11. Zheng Han, Zhihong Feng, Wen Shi, Zhihui Zhao,Yongjiang Wu, Aibo Wu*. A quick, easy, cheap, effective, rugged and safe sample pretreatment-based liquid chromatography tandem mass spectrometry method for simultaneous quantification of 33 mycotoxins in Lentinula edodes. Journal of Separation Sciences (Cover paper), 2014, 37: 1-10.
  12. Zhiyong Zhao, Suquan Song, Na Liu, Qinxiong Rao, Jiafa Hou, De Saeger Sarah, Aibo Wu*. Large-scale preparation and multi-dimensional characterization of high-purity mycotoxin deoxynivalenol in rice culture inoculated with Fusarium graminearum. Analytical Methods, 2014, 6(17): 6651C6657.
  13. Zhiyong Zhao, Qinxiong Rao, Suquan Song, Na Liu, Zheng Han, Jiafa Hou, Aibo Wu*. Simultaneous determination of major type B trichothecenes and deoxynivalenol-3-glucoside in animal feed and raw materials using improved DSPE combined with LC-MS/MS. Journal of Chromatography B, 2014, 963: 75C82.
  14. Na Liu, Suquan Song, Lei Lu, Dongxia Nie, Zheng Han, Xianli Yang, Zhihui Zhao, Aibo Wu*, Xiaodong Zheng*. A rabbit monoclonal antibody-based sensitive competitive indirect enzyme-linked immunoassay for rapid detection of chloramphenicol residue. Food and Agricultural Immunology, 2014, 25(4): 523-534.
  15. Zheng Han, Dongxia Nie, Xianli Yang, Jianhua Wang, Shaojie Peng, Aibo Wu*. Quantitative assessment of risk associated with dietary intake of mycotoxin ochratoxin A on the adult inhabitants in Shanghai city of PR China. Food Control, 2013, 32:490-495.
  16. Zheng Han, Emmanuel K. Tangni, Jos└ Diana Di Mavungu, Lynn Vanhaecke, Sarah De Saeger, Aibo Wu*, Alfons Callebaut. In Vitro Glucuronidation of Ochratoxin A by Rat Liver Microsomes. Toxins, 2013, 5(12): 2671-2685.
  17. Na Liu, Zheng Han, Lei Lu, Lin Wang, Gen Ni, Zhihui Zhao, Aibo Wu*, Xiaodong Zheng*. Development of a new rabbit monoclonal antibody and its based competitive indirect enzyme-linked immunosorbent assay for rapid detection of sulfonamides. Journal of the Science of Food and Agriculture, 2013, 93(3):667-673.
  18. Na Liu, Dongxia Nie, Zheng Han, Xianli Yang, Zhiyong Zhao, Jiner Shen, Gang Liu, Aibo Wu*, Xiaodong Zheng*. Rabbit Monoclonal Antibody-Based Lateral Flow Immunoassay Platform for Sensitive Quantitation of Four Sulfonamide Residues in Milk and Swine Urine. Analytical Letters, 2013, 46(2):286-298.
  19. Zheng Han, Chensen Chi, Bing Bai, Gang Liu, Qinxiong Rao, Shaojie Peng, Hong Liu, Zhihui Zhao, Dabing Zhang, Aibo Wu*. Chromogenic platform based on recombinant Drosophila melanogaster acetylcholinesterase for visible unidirectional assay of organophosphate and carbamate insecticide residues. Analytica Chimica Acta, 2012, 720: 126C133.
  20. Gang Liu, Zheng Han, Junhua Yang, Zhihui Zhao, Jingbo Zhang, Heping Li, Yucai Liao, Suquan Song, Sarah De Saeger, Aibo Wu*. Rapid and sensitive quantitation of zearalenone in food and feed by lateral flow immunoassay. Food Control, 2012, 27: 200-205.
  21. Zheng Han, Gang Liu, Qingxiong Rao, Bing Bai, Zhihui Zhao, Hong Liu*, Aibo Wu*. A liquid chromatography tandem mass spectrometry method for simultaneous determination of acid/alkaline phytohormones in grapes. Journal of Chromatography B, 2012, 881-82:83-89,.
  22. Zheng Han, Zhiyong Zhao, Suquan Song, Gang Liu, Jianxin Shi, Jingbo Zhang, Yucai Liao, Dabing Zhang, Yongjiang Wu, Sarah De Saeger, Aibo Wu*. Establishment of an isotope dilution LC-MS/MS method revealing kinetics and distribution of co-occurring mycotoxins in rats. Analytical Methods, 2012, 4(11):3708-3717.

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